|
Post by kaimelstable on Jul 17, 2011 23:38:45 GMT -5
I read somewhere that the Sabino 1 gene hasn't been found in Arabians and Thoroughbreds. Would anyone happen to know more about that? It just confused me a little bit.
|
|
|
Post by Silence on Jul 18, 2011 0:05:13 GMT -5
From the research I've done, it hasn't. But that doesn't mean Arabians and Thoroughbreds can't be sabino. The sabino 1 gene is so named because scientists fully expect to find more genes that produce the sabino coloring in horses. The sabino one gene is also absent from Clydesdales - and they are they most certainly have the coloring.
|
|
|
Post by kaimelstable on Jul 18, 2011 0:19:46 GMT -5
Alright thats what I thought but what I read just made it sound like they weren't actually sabino or something lol.
|
|
|
Post by Odeon on Jul 18, 2011 0:25:25 GMT -5
I believe that Thoroughbreds are generally referred to as being "Dominant White" not sabino, per se, but I don't really know that much about it. I'd ask someone like Shelly to explain it, if you're curious. She's nuts on this sort of genetic thing.
|
|
shay
Senior Member
Posts: 435
|
Post by shay on Jul 18, 2011 14:54:09 GMT -5
A lot of the thoroughbreds may not be sabino at all but dominant white. Atleast many have been found to carry the dominant white gene (I suppose they could have a sabino gene as well). I found this equinegenetics.blogspot.com/2009/11/dominant-white-not-sabino.html. It lists some of the commonly thought of sabino thoroughbreds that have actually been found to carry the dominant white gene. Also somewhere else on the blog it may have some information on arabians as well...
|
|
|
Post by kaimelstable on Jul 19, 2011 1:06:56 GMT -5
Does anyone have any other links on the subject? I'd really like to see a more serious research paper on the subject. I just have a hard time taking blogs seriously when its all just "I read this" or "I heard that". Isn't there somewhere that has information from an actual study? I've just read too many blogs/posts/websites that appear to know what they are taking about and really are completely wrong.
|
|
|
Post by Tessa on Jul 19, 2011 7:46:17 GMT -5
Wikipedia has something on the subject and it says a lot of the same things...you could try there You may also be able to try horsetesting.com, it may have something on Sabino
|
|
|
Post by Shelly on Jul 19, 2011 13:58:14 GMT -5
I would read this article. It covers everything you asked.
Thoroughbreds carry the Dominant White, Splash, Frame, and Rabicano genes. They do not carry the mapped Sabino-1 gene. As you can see from the article, D.W. can mimic the sabino gene. It is suspected that Puchilingui also carries the splash, based upon some of his offspring.
|
|
|
Post by kaimelstable on Jul 19, 2011 20:26:45 GMT -5
That was more what I was looking for Shelly, thanks.
That was definatly an interesting read. I can't wait for the days when you can actually say for sure if a breed carries a certain color or not. As it stands I'm not too convinced Arabians or Thoroughbreds don't carry Sabino. An interesting tid-bit I found in the article was "predicted to be embryonic lethal when homozygous, are classified as Dominant White. Mutations that are viable in the homozygous state are categorized as Sabino". Sounds like some forms of Dominant White as we know it could be called a variation of Sabino once more testing is done.
|
|
|
Post by Shelly on Jul 19, 2011 22:45:21 GMT -5
Homozygous D.W. kills the foal in the embryonic stage, a homozgyous sabino is nearly all white (some color is retained, but may be hard to find such as in the ear or around the privates...). A homozygous frame (overo) foal (lethal white) dies at birth. So if you bred Puchi and Patchen Beauty together, you'd have a 25% chance of having a dead embryo, 25% of having D.W., and 50% of solid, just like if you bred two frame overos together, but with lethal white, mares carry the foal to term/give birth. I'd never risk that sort of breeding, personally... but some people are just... nuts? >.<
|
|
|
Post by kaimelstable on Jul 20, 2011 10:32:38 GMT -5
I've never actually read anywhere its confirmed that Dominant White is lethal in the homozygous state. Only thats it predicted to be (which is what the quote is saying) because its lethal in mice (which mice studies is what they seem to look to while studying this mutation in horses and is where the term Dominant White comes from or what not). Because they have found no homozygous Dominant White horses they are predicting it to be lethal.
I'm saying I can't wait to see how this all turns out because some horses tested for Dominant White/Sabino turn out negative but still have the white pattern of a Sabino/Dominant White/Splash horse. I'm just guessing with more testing they are going to find more Sabino mutations (like they have with Dominant White). Or if a mutation of Dominant White turns out nonlethal (which I doubt but you never know) then it'd become a type of Sabino by the sounds of it.
|
|